Scientists at the Allen Institute for Neural Dynamics analyze and trace the path of signaling in neural circuits cascading across the whole brain and body.
Our approach is focused on how the parts of the brain work together to produce behavior. Teams of researchers develop next-generation neurotechnologies that capture rich data that are shared with the wider scientific community.
We are doing science in the open. Our data and tools are openly available to the community.
We work in a coordinated manner to address complex and deep scientific challenges, leveraging the joint strengths and expertise of diverse scientists and technical staff.
The Surgery team offers a variety of aseptic rodent surgical procedures ranging from stereotaxic injections to headpost implantation and cranial windowing.
The Neuropixels platform uses pioneering technology for highly reproducible, targeted, brain-wide, cell-type-specific electrophysiology to record neural activity from defined neuron types across the brain.
The Molecular Anatomy platform combines innovative histology, imaging, and analysis techniques to map the morphology and molecular identity of neuron types across the whole brain.
The Behavior platform uses advanced technology to implement a standardized, modular, multi-task virtual reality gymnasium for mice, with the goal to study brain function across different behaviors at scale.
The Fiber Photometry platform enables optical measurement of neural activity in live animals to study neural circuits' function and dynamics in behaving animals.
We are uncovering how neural signals are transmitted from subcortical brain regions via the thalamus to modulate cortical activity and thereby influence behavior.
We are combining longitudinal in vivo calcium imaging with spatial transcriptomics to investigate how specific cell types restructure their activity during novelty processing and task learning.
We are studying task-switching behaviors in mice to determine how the brain controls the flow of its own activity and how neuronal circuits are reconfigured to dynamically route information for different tasks.